In Vivo Human Study

Controlled human observational study involving 70 participants demonstrating reduced alcohol-related symptoms and improved liver biomarker stability following Alcotox consumption.

Study Overview

A controlled human study involving 70 participants evaluated the effects of Alcotox during alcohol consumption.

Biomarkers, physiological responses and self-reported symptoms were measured to assess the impact of Alcotox under real-world drinking conditions.

Study Design

Participants consumed alcohol under real-world drinking conditions, both with and without Alcotox. Physiological measurements and symptom questionnaires were recorded to evaluate the effects of alcohol consumption and the potential impact of Alcotox.

Outcomes included liver enzyme biomarkers, cognitive performance testing and participant-reported hangover symptoms.

Key Data

Blood panels measured liver enzyme biomarkers including ALT, AST and GGT. Participants also completed a digital cognitive performance assessment the following morning.

Standardised questionnaires were used to record participant-reported hangover symptoms.

Study Results

Alcohol consumption produced measurable physiological responses in the control condition. Participants consuming alcohol with Alcotox showed improved biomarker stability, preserved cognitive performance and reduced hangover symptom severity.

Liver Biomarkers

Blood samples were collected before and after alcohol consumption and analysed for key liver enzyme biomarkers including ALT, AST, CK and GGT.

Biomarker levels were compared between participants consuming alcohol alone and those consuming alcohol with Alcotox supplementation.

Dose Response

ALT levels were analysed relative to the amount of alcohol consumed during the study event.

Individual biomarker responses were plotted against ethanol intake to compare participants consuming alcohol alone with those receiving Alcotox supplementation.

Hangover Incidence

Participants reported whether hangover symptoms occurred following alcohol consumption.

Hangover symptoms were reported by 13.6% of participants consuming alcohol with Alcotox compared with 65.4% of participants consuming alcohol without supplementation.

Conclusion

This observational human study evaluated the physiological effects of alcohol consumption when Alcotox supplementation was used under real-world drinking conditions.

Across the study population, participants consuming alcohol without supplementation demonstrated the expected increases in liver enzyme biomarkers following alcohol intake. Participants receiving Alcotox showed a more stable biomarker profile, with reduced changes in several liver enzyme markers and lower ALT responses across varying levels of alcohol consumption. These effects were somewhat more pronounced among female participants.

Self-reported questionnaires also indicated a substantially lower incidence of hangover symptoms among participants consuming Alcotox compared with those consuming alcohol alone. The full results of the 70-participant observational study are available in the published paper:

View the Published Study on ResearchGate

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