Harley Street Human Pilot Study

An exploratory clinical evaluation conducted with a Harley Street clinic in London monitored physiological responses to alcohol consumption with Alcotox under controlled drinking conditions.

Blood biomarkers including ALT, AST and Gamma-GT were measured before drinking and the following day alongside cognitive performance assessments.

Study Protocol

Participants consumed substantial quantities of alcohol during monitored drinking sessions. Blood biomarkers including ALT, AST and Gamma-GT were measured before drinking and again the following day to assess liver function response.

Cognitive performance testing and symptom questionnaires were also recorded during the evaluation.

Alcohol Consumption During Test

  • Heavy Alcohol Intake

    Participants consumed substantial quantities of alcohol during the monitored session, averaging approximately 18–19 UK units per participant.

  • Pure Alcohol Exposure

    This equates to approximately 145–155 grams of pure ethanol, representing a level of intake significantly above typical daily consumption.

  • Purpose of Test

    The goal was to observe physiological responses to meaningful alcohol exposure, ensuring biomarker measurements reflected realistic drinking conditions.

Liver Enzyme Panel

Blood tests measured key liver enzymes (ALT, AST and GGT) before alcohol consumption and again the following day.

Despite substantial alcohol intake, enzyme levels remained within normal clinical ranges across all participants.

Cognitive Test

Participants completed a digital cognitive function assessment the morning after alcohol consumption.

Results showed performance within or above the normal range for age, indicating preserved cognitive function despite alcohol intake.

Conclusion

This pilot investigation conducted at a Harley Street clinic explored the physiological and cognitive effects of alcohol consumption when Alcotox was used.

Across participants, key liver enzyme markers (ALT, AST and GGT) remained within normal clinical ranges following alcohol consumption. Cognitive performance testing the following morning also remained within the normal range, and self-reported symptom questionnaires indicated generally mild hangover symptoms.

While limited to four participants, this pilot provided early real-world observations suggesting that Alcotox may help mitigate some of the physiological and functional effects commonly associated with alcohol consumption.

To further investigate these effects, a larger controlled human study involving 70 participants was subsequently conducted and published. The results of that study provide a more comprehensive evaluation of Alcotox in real-world drinking conditions.

View the Published 70-Participant Study

View the Laboratory Acetaldehyde Study