In Vitro Acetaldehyde Study

Select Pharma laboratories conducted the following study to investigate the effects of Alcotox on reducing the acetaldehyde levels of common alcoholic beverages. The dosage used was standard 975 mg Alcotox ( 1 size 00 capsule ) and 1 standard drink equivalent of the alcoholic beverage under test.

Study Date : 5 October 2012

Study Objectives: To investigate the effects of Alcotox on reducing acetaldehyde levels in wine.

Method: 125 ml of white wine at 12.5% alcohol concentration was used in the test. The measured baseline acetaldehyde level was 44 mg/litre. To simulate stomach acid conditions, the white wine was mixed with hydrochloric acid solution and incubated for 90 minutes at 37 degrees Celsius. Single and double dose of 975 mg of Alcotox was administered and subsequent acetaldehyde levels were measured. Each test was run in duplicate.

Results: A single dose of 975 mg Alcotox reduced acetaldehyde present in the white wine by 86.8%, from baseline 44 mg/l to 5.8 mg/l.

Conclusions: The results are overwhelmingly conclusive and demonstrate the powerful ability of Alcotox to target, scavenge and neutralise acetaldehyde.  The results justify further research into the Alcotox effect.

 

Alcotox In Vivo Human Study

We’ve now published the results of our first large-scale human study evaluating Alcotox™ in a real-world setting. Conducted with 70 adult participants, this controlled observational trial found that Alcotox™ significantly mitigated alcohol-related harm on two key fronts. First, liver function improved: ALT levels dropped significantly (38.91 → 31.97 U/L; P < 0.003) in the Alcotox™ group, while control participants saw liver enzyme elevations after alcohol. Second, participants who took Alcotox™ experienced a 4.8x lower incidence of hangover symptoms (13.6% vs. 65.4%; P < 0.01). These results support Alcotox’s mechanism of action - reducing acetaldehyde exposure - and its potential as a clinically relevant tool to protect the liver and improve recovery after drinking.

Read the full study here:
https://www.researchgate.net/publication/394088514